Amyopathic Dermatomyositis–Related Thrombophilia

Erosive arthropathy in amyopathic dermatomyositis.

Sirs, Articular symptoms are reported in 25-50% p atients with idiopathic infl a m m at o ry myopathies (IIM) (1,2). Arthropathy in IIM is typically symmetri c a l , n o n d e fo rm i n g and non-erosive (1-4). A subluxing arthropathy, which may be associated with eros i o n , has been described in IIM pat i e n t s with anti-synthetase antibodies (2, 4-9). We report a patient with amyopathic d...

Cutaneous amyloidosis associated with amyopathic dermatomyositis.

Panniculitis associated with amyopathic dermatomyositis*

Panniculitis is a rare clinical finding in dermatomyositis, with less than 30 cases reported and there is only one case associated with the amyopathic subtype described in the literature. The present report describes a 49-year-old female patient that one year after being diagnosed with amyopathic dermatomyositis, presented indurated, painful, erythematous to violaceous nodules located on the up...

How Often are Pediatric Patients with Clinically Amyopathic Dermatomyositis Truly Amyopathic?

BACKGROUND Pediatric patients can present with skin manifestations of dermatomyositis without overt weakness (clinically amyopathic juvenile dermatomyositis [JDM]), but it is unclear how often this happens and how often they have subclinical muscle inflammation. OBJECTIVE Our goal was to determine the frequency of clinically amyopathic JDM and the frequency with which a thorough evaluation un...

Hereditary thrombophilia

Thrombophilia can be defined as a predisposition to form clots inappropriately. Thrombotic events during infancy and childhood are increasingly recognized as a significant source of mortality and morbidity. The predisposition to form clots can arise from genetic factors, acquired changes in the clotting mechanism, or, more commonly, an interaction between genetic and acquired factors. Since the...